Keep me, O Lord, from the hands of the wicked,.... From falling into their hands, and the weight of them); and from their laying hands on him, being men of power and authority; preserve me from the violent man: or men, everyone of them; See Gill on Psa 140:1; who have purposed to overthrow my goings: to supplant him; to cause him to stumble and fall, to his disgrace and reproach; and that they might take an advantage of him, and an occasion against him. Arama interprets it, to drive me out of the land of Israel; see Sa1 26:1. So Christ's enemies thought to have supplanted him, and have found something against him, to accuse him of to Caesar, Mat 22:15.