Jerome : (Verse 1) And now, thus says the Lord, the one who created you, Jacob, and the one who formed you, Israel: Do not fear, for I have redeemed you; I have called you by name, you are mine. LXX: And now thus says the Lord who made you, Jacob, and formed you, Israel: Do not fear, for I have redeemed you; I have called you by your name, you are mine. The Hebrews interpret this as the second coming of the Savior, when after the fullness of the Gentiles, all of Israel will be saved. But we do not think that the promise will be fulfilled for them, as it has been said: Who is blind, but my children? And who are deaf, but those who rule over them? And the servants of God have become blind. And again: The people have been devastated and plundered, and similar things. Finally he brought upon him the outpouring of his furious indignation, and perhaps war, and consumed him all around, and did not recognize, and set him ablaze, and did not understand. Therefore, what we have said above, there are two Jacobs and two Israels, one carnal and the other spiritual, those who did not want to believe in the Savior and those who received the Son of God. This should also be understood now, that the chorus of the Apostles and the first Church of Christ, gathered from the Jewish people, may understand their Creator and Maker, who is both the creator of their soul and body. And let him not fear persecutors, because he has been redeemed by the blood of Christ, who has called him by his name, and let him specifically call his people because of their special relationship; but let him preach fearlessly, and let him not fear any dangers. — Commentary on Isaiah Procopius of Gaza : The things said here are of a quite different tenor from what was said in the previous passage about the people of the covenant, where he called them blind, deaf and plundered. Now the message here is of the better condition of those believers of the covenant who belong to a better order. For the former ones were those who were suffering. Here he addresses as "you" those who recognize their Creator and Maker. "Do listen to the one who keeps you an unblemished creation and product, for here you are fittingly called Jacob and Israel. For I made you in your soul, according to the image, and formed you, taking a body from the ground, and I provided my blood for you, buying back my own creation. You, being made worthy of these things, go by the road on which you are instructed to go and preach the good news. Although some will attack you, be encouraged that you are special. 'For behold, I am with you always, even to the end of the age.' Be followers of me, the one who wished to give my blood of redemption for you, as atonement." …"You are mine." For we are said to have been Christ's, even before the separation from God that occurred when we as sinners went out of the garden, though by nature we were always God's. But he has made us once more to be his own through the Holy Spirit making us strong through every trial. Rivers, water and flames denote the many channels of temptation. For it is written, "All who wish to live godly lives in Christ Jesus will be persecuted." And Christ says to those who believed in him, "You will have sorrow in the world." — COMMENTARY ON Isaiah 43:1-13