Didymus the Blind : The one who has been united to the Holy Spirit has been bound in him so that he does not separate from the Spirit in any way. The person of such a disposition is a captive of Christ whose Spirit he has. For if whoever does not have the Spirit of Christ is not of Christ, who has the Spirit, it is clear that whoever has Christ is in the Spirit. Whoever is bound and decorated with these chains begets, by both the gospel's and his own chains, those he teaches.… This verse must be read in respect to the following, which says that the apostle is ready to be clothed with chains because of his beliefs. When it is said to him that he must not go up to Jerusalem, since there he will certainly be covered with chains and afflictions, he says that he is bound in the Spirit now to make his way to Jerusalem in full knowledge of what would befall him there. His words, "Daily I die," are a manifestation of this determination of his, as are his words, "Ever are we, while living, handed over to death because of Christ Jesus." To this you can add the words of the psalmist, "I am ready to be scourged." — CATENA ON THE ACTS OF THE APOSTLES 20.22 John Chrysostom : To what end, then, sayest thou these things? to what end dost thou put them in mind of them? What has come of it? hast thou anything to lay to their charge? Having first alarmed their feeling, then he adds, "And now, behold, I go bound in the Spirit unto Jerusalem, not knowing the things that shall befall me there: save that the Holy Ghost witnesseth in every city, saying that bonds and afflictions abide me." Wherefore says he this? By way of preparing them to be always ready to meet dangers, whether seen or unseen, and in all things to obey the Spirit. He shows that it is for great objects that he is led away from them. "Save that the Holy Ghost," he says, me, "in every city witnesseth to me saying"-to show that he departs willingly; that you may not imagine it any bond or necessity, when he says, "bound in the Spirit-that in every city bonds and afflictions await me." — Homily on Acts 44 John Chrysostom : "Not knowing," he says, "the things that shall befall me." Then is this why thou departest? By no means; on the contrary (I know that), "bonds and afflictions await me." That (there are) trials, I know, but of what kind I know not: which was more grievous. — Homily on Acts 44 Oecumenius : Here, in the passage "bound," it is necessary to insert, so that either the mind be such: I am going to Jerusalem, having foreknowledge through the Spirit of the things that will be; and yet I go as a prisoner. Then, for fear that anyone suppose it is bondage or compulsion, and to show that he departs willingly, he says that "in every city, saying that bonds and afflictions await me." "I am innocent," he says, "of the blood of all men," if you, being drowsy, perish because of the murderer of souls; for of the teacher, he says, For I did not shrink from declaring to you the whole counsel of God. Therefore he who does not speak is responsible for their blood, that is, for their slaughter. He therefore shows that even those who do not act would be responsible for that same blood; and on that account he exhorts them. — Commentary on Acts