Help me, O Lord my God,.... Jehovah the Father is here addressed, who is the God of Christ, as Christ is man; who formed him, supported him, and glorified him; and whom Christ loved, believed in, obeyed and prayed unto; nor did he pray to a God that could not hear, but to one that was able to save him from death: as a divine Person he needed no help, being the mighty God, the most Mighty, the Almighty: but as man he did, being encompassed about with infirmities; and as Mediator help was promised him, he expected it, and he had it, Psa 89:21. O save me according to thy mercy; or "kindness"; as before in Psa 109:21 from sufferings, and out of them; from death and the grave, as he was; or his people by him, who are saved not by works of righteousness, but according to the mercy of God, Tit 3:5.