Jerome : How does the blessing refer to the letter? Not discord, not slavery to the law, not biting and railing, but the grace of the Lord Jesus Christ is asked to be "with your spirit." Not with the flesh only; not with the soul only. For having been made spiritual they have ceased to be cheaply embodied. In the Spirit both body and soul are embraced. The grace of the Lord Jesus is not given indiscriminately to all but to those who are ready to be called brothers by the apostle—faithful brothers and intimate brothers, as the word amen signifies in Hebrew. — EPISTLE TO THE Galatians 3.6.18 Jerome : (Verse 18) The grace of our Lord Jesus Christ be with your spirit, brothers. Amen. There is no dissension, no bondage to the Law, no quarrel, no dispute, but rather may the grace of our Lord Jesus Christ be with your spirit. Not at all with the flesh, not at all with the soul; whether because you have become spiritual, or because even those things that are lesser are included in the principal. For the soul and the flesh are subject to the spirit. Regarding this, both the Ecclesiastes and Paul speak: 'The spirit will return to the one who gave it' (Eccl. XII, 7). And Paul in another place: 'The Spirit himself bears witness with our spirit' (Rom. VIII, 16). But this grace of the Lord Jesus is not with everyone, but with those who deserve to be called brothers by the apostle, faithful brothers, and true brothers, which the Hebrew word Amen signifies. For Amen, the Septuagint interpreters have translated as 'let it be'; Aquila, Symmachus, and Theodotius have faithfully and truly interpreted it. And how God confirms his words in the Old Testament through a certain custom of swearing, saying, 'As I live,' says the Lord (Num. XIV, 28); he also swears by the saints: 'As your soul lives'; so too our Savior in the Gospel demonstrates by the word 'Amen' that what he speaks is true. And indeed, 'Amen' signifies the consent of the hearer and is a seal of truth, as the first letter to the Corinthians also teaches us, in which Paul says: 'But if you bless with the Spirit, who supplies the place of the untaught?' How can someone say 'Amen' to your blessing if they do not understand what you are saying? (I Cor. XIV, 16) This shows that an ignorant person cannot respond truthfully to what is being said unless they understand what is being taught. — Commentary on Galatians John Chrysostom : "The grace of our Lord Jesus Christ be with your spirit, brethren. Amen." By this last word he hath sealed all that preceded it. He says not merely, "with you," as elsewhere, but, "with your spirit," thus withdrawing them from carnal things, and displaying throughout the beneficence of God, and reminding them of the grace which they enjoyed, whereby he was able to recall them from all their judaizing errors. For to have received the Spirit came not of the poverty of the Law, but of the righteousness which is by Faith, and to preserve it when obtained came not from Circumcision but from Grace. On this account he concluded his exhortation with a prayer, reminding them of grace and the Spirit, and at the same time addressing them as brethren, and supplicating God that they might continue to enjoy these blessings, thus providing for them a twofold security. For both prayer and teaching, tended to the same thing and together became to them as a double wall. For teaching, reminding them of what benefits they enjoyed, the rather kept them in the doctrine of the Church; and prayer, invoking grace, and exhorting to an enduring constancy, permitted not the Spirit to depart from them. And He abiding in them, all the error of such doctrines as they held was shaken off like dust. — Homily on Galatians 6 Oecumenius : "with your spirit." With a mindful spirit. He wishes to attain favor for his soul. — Commentary on Galatians