Thou holdest mine eyes waking,.... Or, "the watches", or rather "keepers of the eyes" (m); the eyebrows, which protect the eyes; these were held, so that he could not shut them, and get any sleep; so R. Moses Haccohen interprets the words, as Jarchi observes; and so the Targum, "thou holdest the brows of my eyes;'' a person in trouble, when he can get some sleep, it interrupts his sorrow, weakens it at least, if it does not put a stop to it; wherefore it is a great mercy to have sleep, and that refreshing, Psa 127:1, but to have this denied, and to have wearisome nights, and be in continual tossing to and fro, is very distressing: I am so troubled that I cannot speak; his spirits were so sunk with weariness, and want of sleep in the night, that he could not speak in the morning; or his heart was so full with sorrow, that he could not utter himself; or it was so great that he could not express it; or his thoughts were such that he dared not declare them; or he was so straitened and shut up in himself that he could not go on speaking unto God in prayer. (m) "vigilias", Pagninus, Montanus, Vatablus, Tigurine version; "palpebras oculorum meorum", Musculus, Cocceius; "palpebras quasi custodias oculorum", Michaelis.