And he arose out of the synagogue,.... That is, when he had dispossessed the unclean spirit, he rose up, and went out of the synagogue: and entered into Simon's house; the house of Simon Peter, and which was also Andrew's; and in Beza's ancient copy, and in one of Stephens's, it is added, "and of Andrew"; who, though they were both natives of Bethsaida, yet, it seems, had an house at Capernaum, whither Christ went of his own accord, or by an invitation given him: and Simons wife's mother was taken with a great fever. The Vulgate Latin version reads, "with great fevers". The fever is "a disease, or rather a class of diseases, whose characteristic is a preternatural heat felt through the whole body, or, at least, the principal parts thereof, attended with other symptoms----"One" defines a fever, a strenuous endeavour, or effort of nature to throw off some morbific matter, that greatly incommodes the body.---- "Another", an augmented velocity of the blood; others, a fermentation of the blood; accompanied with a quick pulse and excessive heat.----The causes of fevers are innumerable, and the disease even often arises in the soundest bodies, where there was no previous morbific apparatus, as cachochymia, plethora, &c. but merely from a change of air, food, or other alteration in the non-naturals. A fever, "one" observes, is an inseparable companion of an inflammation. The symptoms are many: every fever, arising from any internal cause, is attended with a quick pulse, and unusual heat at different times, and in different degrees. Where these are intense, the fever is acute, where remiss, slow. The disease begins almost always with a sense of; chillness, and in its progress is chiefly distinguished by the velocity of the pulse: so that a too quick contraction of the heart, with an increased resistance, or impulse against the capillaries, furnishes the proper idea of a fever (z).'' The fever Peter's wife's mother lay ill of, is said to be a "great one"; which circumstance is the rather mentioned, to illustrate the miraculous cure of it by Christ; See Gill on Mat 8:14. And they besought him for her; either his disciples Peter, Andrew, James, and John, who were all present, or the other relations and friends of the sick person, which were in the house; who having heard of his casting out the unclean spirit in the synagogue, believed that he had power to heal this disease; and therefore intreat him, for her sake, and upon her account, that he would restore her health. (z) See Chambers's Cyclopaedia in the word "Fever".