Jerome : (Verses 21, 22.) And Isaiah commanded them to take a lump of figs and apply it to the boil, and he would be healed. And Hezekiah said that the sign would be that he would go up to the house of the Lord. This should be read before Hezekiah's prayer, or Scripture, which we have just interpreted: for the poultice was applied to the wound first, and the sign of future healing was requested from him before he thanked the Lord for healing him. The Hebrews say that the word Siin (), which the LXX omitted, means ulcer and not wound. For both Aquila and Symmachus and Theodotion have interpreted it as sore, by which they want to understand a royal disease, which they think is contrary to, whether it is taken in food, or whatever sweet things are applied to the body. Therefore, in order to demonstrate the power of God, health is restored through harmful and adverse things. Others suspect Siin to be not an ulcer, but an abscess: when the body swells and becomes putrid, it is filled with pus. According to the art of doctors, all pus is drawn to the surface of the skin by applying dried and crushed figs: and therefore medicine should not be despised, which is based on use and experience: because God made this also. Therefore, the speech and expression of thanks have been written up to this point. But as for the sign that was given, the previous order of the story has narrated it. — Commentary on Isaiah