Jacob was sent by his parents to Mesopotamia that he might take a wife there. These were his father's words on sending him: "Thou shalt not take a wife of the daughters of the Canaanites. Arise, fly to Mesopotamia, to the house of Bethuel, thy mother's father, and take thee a wife from thence of the daughters of Laban thy mother's brother. And my God bless thee, and increase thee, and multiply thee; and thou shalt be an assembly of peoples; and give to thee the blessing of Abraham thy father, and to thy seed after thee; that thou mayest inherit the land wherein thou dwellest, which God gave unto Abraham." Now we understand here that the seed of Jacob is separated from Isaac's other seed which came through Esau. For when it is said, "In Isaac shall thy seed be called," by this seed is meant solely the city of God; so that from it is separated Abraham's other seed, which was in the son of the bond woman, and which was to be in the sons of Keturah. But until now it had been uncertain regarding Isaac's twin-sons whether that blessing belonged to both or only to one of them; and if to one, which of them it was. This is now declared when Jacob is prophetically blessed by his father, and it is said to him, "And thou shalt be an assembly of peoples, and God give to thee the blessing of Abraham thy father."