She sent out her boughs unto the sea,.... The Mediterranean, or midland sea, which was the border of the land of Canaan to the west: and her branches unto the river; the river Euphrates, which was its border to the east; see Deu 11:24. This, in the spiritual sense of it, will have its accomplishment in the church of Christ, when he shall have dominion from sea to sea, and from the river to the ends of the earth, Psa 72:8. The Targum is, "she sent out her disciples to the great sea, and to the river Euphrates her babes;'' or sucklings.