And Aaron shall make an atonement upon the horns of it once in a year,.... On the day of atonement, as the Targum of Jonathan, and so Jarchi and Aben Ezra explain it; and the atonement here referred to seems to be an atonement for the altar itself, see Lev 16:18 and as the altar of burnt offering was first expiated and then used, Exo 29:36 so it seems the altar of incense had not only an atonement made on it, but for it: and this was done with the blood of the sin offering of atonement; by sprinkling the blood of that offering upon the horns of it, as we learn from the afore mentioned place; and this shows that Christ's mediation and intercession is founded upon the virtue of his blood, and the efficacy of his atoning sacrifice, see Jo1 2:1. once in the year shall he make atonement upon it, throughout your generations; which proves the insufficiency of all legal sacrifices of themselves to take away sin, since every year, as the apostle observes, there was a remembrance of it, Heb 10:3. it is most holy unto the Lord; either the atonement made on the day of atonement, which was a most holy part of service, and pointed at the great atonement made by the most Holy One, the Son of God; or this altar thus expiated, and devoted to sacred use, was reckoned a most sacred one to the Lord, and so was to have nothing offered upon it but what he ordered; with which Jarchi agrees in his note,"the altar is sanctified to these things only, and not to any other service.''