The wisdom of the prudent is to understand his way,.... The way of his calling, in which he should abide, and how to manage it in the best manner; the way of his duty, that he may walk inoffensively both towards God and men; and the way of life and salvation, which is by Jesus Christ, which to understand and to walk in is the highest wisdom and prudence; but the folly of fools is deceit: or "the wisdom of fools", which the opposition requires, and is meant, and is what the Holy Ghost calls "folly", as elsewhere, Co1 3:19; this is itself "deceit"; it is science, falsely so called; it lies in tricking and deceiving; and the issue of it is, not only the deceiving of others, but themselves also: such is the folly of the man of sin and followers, which lies in deceiving the inhabitants of the earth with their sorceries and superstitions, with their lying wonders and miracles; see Th2 2:10, Rev 13:14.