Because I have called, and ye refused,.... This is to be understood not of the internal call of Wisdom, or Christ, which is by the special grace of his Spirit; is according to an eternal purpose, the fruit of everlasting love, peculiar to God's elect, and by a divine power; and is also a call to special blessings of grace, and to eternal glory; and which is always effectual, unchangeable, and irreversible, and can never be refused, rejected, and resisted, so as to become void and of no effect: but of the external call by the word, to the natural duties of religion, and to an attendance on the means of grace; which may be where no election goes before, no sanctification attends, nor salvation follows, Mat 20:16; and this may be refused and rejected, as it often is; as when men, notwithstanding that call, do not attend on the ministry of the word, or, if they do, it is in a negligent careless way; or, they show an aversion to it, despise, contradict, and blaspheme it, as the Jews did, who were the persons first called to hear it; see Mat 22:2; I have stretched out my hand, and no man regarded; this is a gesture of persons calling to others, as orators and preachers, requiring silence and attention; and when eager and fervent, and importunate in their discourses; it is attributed to Christ, Isa 65:2; but, notwithstanding all Wisdom's eagerness, zeal, warmth, and importunity, expressed by words and gestures, it was all disregarded; no attention was given to it, which is here complained of.