Therefore shall ye lay up these my words in your heart, and in your soul,.... Treasure up the laws of God delivered to them in their minds, retain them in their memories, and cherish a cordial affection for them; which would be an antidote against apostasy, idolatry, and other sins, Psa 119:11. and bind them for a sign upon your hand, that they may be as frontlets between your eyes; of this and the two following verses; see Gill on Deu 6:7; see Gill on Deu 6:8; see Gill on Deu 6:9.