Jerome : (Verses 23-24) You did not offer me the ram of your burnt offering, and you did not glorify me with your sacrifices. I did not make you serve in the offering, nor did I require labor from you in the burning of incense. You did not buy for me fragrant reeds with silver, and you did not satisfy me with the fat of your sacrifices. However, you served me in your sins: you provided labor for me in your iniquities. LXX: You have not brought me the sheep of your holocaust; nor have you magnified me with your sacrifices; nor have you made me serve with your offerings; nor have you bestowed upon me labor with frankincense; nor have you purchased for me with silver the sweet odor of your sacrifices; nor have you desired the fat of your victims; but you have defended yourself in your sins, and in your iniquities. But what you think you offered me as victims and sacrificed rams, know that they were not accepted by me, because they were common to me and idols. And he repeats the sense that he stated above: Why do I need the multitude of your victims, says the Lord? I am full of burnt offerings of rams, and fat of lambs, and blood of bulls and goats I do not desire. For I have not required anything precious from you, that I would make you labor in acquiring them. I have not required offerings from you, nor have I sought incense: not reed, nor incense, nor diverse kinds of pigments, with which you would intoxicate and satisfy me with their smoke. But I desired obedience, which is above sacrifice: and sacrifice, of which David says in the Psalms: Sacrifice to God is a contrite spirit: a broken and humbled heart God does not despise (Ps. 50:19), that is what I wanted, that is what I sought. But you have made me serve and labor in your sins, so that I am compelled to say: I have labored and endured; and I can no longer bear you. And through Hosea, God says the same: What shall I do to you, Ephraim? I will protect you, Israel. What shall I do? I will make you like Adam, and like Sodom. But what the Septuagint has is, I have defended you in your sins, and in your iniquities, so it can be connected to the previous statements, that it is God's labor and weariness to defend sinners. — Commentary on Isaiah