The Lord taketh my part with them that help me,.... With the four hundred men that were with David, and stood by him in his troubles, Sa1 22:2; see Psa 54:4; and with those who ministered unto Christ as man, Luk 8:3. Or, "the Lord is for me, with" or "among my helpers" (t); he is the principal helper, he is one for all; he is in the room and stead of other helpers; having him, there is no need of any other: the Lord is the only helper of his people, vain is the help of man; he helps them out of all their troubles and difficulties, in the exercise of every grace, and in the discharge of every duty; he helps them to all their mercies temporal and spiritual, to grace here, and glory hereafter. The Targum is, "the Word of the Lord is to help me;'' therefore shall I see my desire upon them that hate me; see "vengeance" on them, as the Targum; which was desired by David, by the Messiah, and by the saints; not for the sake of that itself, but for the glory of divine justice. David saw this, Psa 54:7; so will the Messiah, when all his enemies, that will not have him to reign over them, will be slain before him; and so will the people of God, when antichrist is destroyed. (t) "pro me est cum iis qui auxiliantur mihi", Vatablus; so Cocceius, Gejerus.