When your fear cometh as desolation,.... When such will be the calamity that will occasion this fear, that it shall be like some desolating judgment, as famine, sword, and pestilence, which lays all waste: and such was the destruction of the Jews by the Romans; it not only laid Jerusalem and the temple waste, but the whole country of Judea. These are the "desolations" said to be "determined", or "the consummation and that determined", which should be "poured upon the desolate", Dan 9:26; and your destruction cometh as a whirlwind; suddenly and unthought of, fierce, and boisterous, throwing down and carrying all before it: so the said destruction did; it threw down the walls and houses of the city of Jerusalem, and the temple, and its fine buildings, so that not one stone was left upon another not thrown down, Mat 24:2; when distress and anguish cometh upon you; as they did at that time with a witness, when Jerusalem was besieged by the Romans: what with the sword of the enemy without, and the famine within; together with the vast number of cutthroats and seditious persons among themselves; it was such a time of distress and tribulation as never was from the beginning of the world, nor ever will be, Mat 24:22. Josephus's history of those times is a proper comment on these words.