But woe unto them that are with-child,.... See Gill on Mat 24:19. For there shall be great distress in the land; of Judea. The Greek word here used, properly signifies "necessity", but here intends afflictions and distress; in which sense it is often used by the Septuagint, as in Psa 107:6 and it is also by the Targumists adopted into their language, and used in the same sense (d): and indeed, the distress was very great, and such a time of tribulation, as was never known since the beginning of the world, nor never will be the like; what with the enemy without, and their seditions and divisions within, the robberies, murders, and famine, which prevailed and abounded, their miseries are not to be expressed: and wrath upon this people; of the Jews; even the wrath of God, as well as of man, which came upon them to the uttermost; and their own historian observes, that God, who had condemned the people, turned every way of salvation to their destruction (e). (d) Vid. Targum in Gen xxii. 14. & xxxviii. 25. & Targum Sheni in Esth. v. 1. (e) Joseph. de Bello Jud. l. 6. c. 15.