Augustine of Hippo : It is quite possible that when Adam was divinely inspired to say, after Seth was born, "God has given me another seed, for Abel whom Cain slew," there is no implication here that Seth was the next born in the order of time but only that he was destined to be a fit heir in the order of holiness. — City of God 15.15 Bede : And Adam knew his wife again, and she bore a son, and he called his name Seth, saying: God has appointed for me another offspring instead of Abel. After he mentioned the fratricide Cain being extinguished, and repeated that his progeny was cursed in the seventh generation, he returns to explain the restoration of the holy seed, and that this remained perpetually despite the perishing of the impious. Now Seth is interpreted as "appointed" or "resurrection," the reason for the name being revealed by the parent saying: — Commentary on Genesis (Hexaemeron) Bede : The Lord has appointed for me another offspring instead of Abel, whom Cain killed. He was appointed in place of Abel, not only in the order of birth but also in the merit of virtue, filling the place of his brother, whose devotion of mind is shown to have also passed to his offspring, as it is added: — Commentary on Genesis (Hexaemeron) Clement of Alexandria : We agree that weakness of will and sexual immorality are passions inspired by the devil. But the harmony of responsible marriage occupies a middle position. When there is self-control, it leads to prayer; when there is reverent bridal union, to childbearing. At any rate, there is a proper time for the breeding of children, and Scripture calls it knowledge, in the words "Adam knew his wife Eve, and she conceived and bore a son, and called him by the name of Seth, 'for God has raised up for me another child in Abel's place.' " — The Stromata Book 3 Cosmas Indicopleustes : And when she had conceived, she bare a son and called his name Sêth, for, said she, God hath raised me up another seed instead of Abel whom Cain slew; implying by this that Abel has died childless, and the seed of Cain is to perish; this hath God given me as a new foundation for the human race. So far Eve. — The Christian Topography, Book 5 Jerome : (Verse 25) And he called his name Seth. For God has provided me another offspring in place of Abel, whom Cain killed. Seth, properly θέσις, that is, position, is called because God had set him in place of Abel. Finally, Aquila says: And he called his name Seth, saying: For God has placed another offspring for me. — Hebrew Questions on Genesis