1 Tim. vi. 20.  The intellectual championship of Basil was chiefly asserted in the vindication of the consubstantiality of the Spirit, against the Arians and Semi-Arians, of whom Euonomius and Macedonius were leaders, the latter giving his name to the party who were unsound on the third Person of the Trinity, and were Macedonians as well as Pneumatomachi.  But even among the maintainers of the Nicene confession there was much less clear apprehension of the nature and work of the Spirit than of the Son.  Even so late as 380, the year after St. Basil’s death, Gregory of Nazianzus, Orat. xxxi. de Spiritu Sancto, Cap. 5, wrote “of the wise on our side some held it to be an energy, some a creature, some God.  Others, from respect, they say, to Holy Scripture, which lays down no law on the subject, neither worship nor dishonour the Holy Spirit.”  cf. Schaff’s Hist. of Christian Ch. III. Period, Sec. 128.  In Letter cxxv. of St. Basil will be found a summary of the heresies with which he credited the Arians, submitted to Eusthathius of Sebaste in 373, shortly before the composition of the present treatise for Amphilochius.